Browsing by Author "Sahin, Fikrettin"
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Antioxidant and antimicrobial properties of the lichens Cladonia foliacea, Dermatocarpon miniatum, Everinia divaricata, Evernia prunastri, and Neofuscella pulla
Aslan, Ali; Gulluce, Medine; Sokmen, Munevver; Adiguzel, Ahmet; Sahin, Fikrettin; Ozkan, Hakan (TAYLOR & FRANCIS LTD, 2006)The aim of this study was to investigate in vitro antimicrobial and antioxidant activities of the methanol extracts of Cladonia foliacea Willd. Hudson, Dermatocarpon miniatum (L.) Mann., Everinia divaricata (L.) Ach., ... -
Synthesis, Cytotoxicity, and Pro-Apoptosis Activity of Etodolac Hydrazide Derivatives as Anticancer Agents
Cikla, Pelin; Ozsavci, Derya; Bingol-Ozakpinar, Ozlem; Sener, Azize; Cevik, Ozge; Ozbas-Turan, Suna; Akbuga, Julide; Sahin, Fikrettin; Kucukguzel, S. Guniz (WILEY-V C H VERLAG GMBH, 2013)Etodolac hydrazide and a novel series of etodolac hydrazide-hydrazones 315 and etodolac 4-thiazolidinones 1626 were synthesized in this study. The structures of the new compounds were determined by spectral (FT-IR, 1H NMR, ... -
Synthesis, Molecular Docking and Anticancer Activity of Diflunisal Derivatives as Cyclooxygenase Enzyme Inhibitors
Coskun, Goeknil Pelin; Djikic, Teodora; Hayal, Taha Bartu; Turkel, Nezaket; Yelekci, Kemal; Sahin, Fikrettin; Kucukguzel, S. Guniz (MDPI, 2018)Cyclooxygenase enzymes play a vital role in inflammatory pathways in the human body. Apart from their relation with inflammation, the additional involvement of COX-2 enzyme with cancer activity was recently discovered. In ... -
Synthesis, Molecular Modelling and Antibacterial Activity Against Helicobacter pylori of Novel Diflunisal Derivatives as Urease Enzyme Inhibitors
Coskun, Goknil Pelin; Djikic, Teodora; Kalayci, Sadik; Yelekci, Kemal; Sahin, Fikrettin; Kucukguzel, S. Guniz (BENTHAM SCIENCE PUBL LTD, 2019)Background: The main factor for the prolongation of the ulcer treatment in the gastrointestinal system would be Helicobacter pylori infection, which can possibly lead to gastrointestinal cancer. Triple therapy is the ...